international workshop
ONYGENALES 2020
10. - 11. September
PRAGUE
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Basic and clinical research advances in dermatophytes and dimorphic fungi.

Target Attendees

The workshop is primarily organized by ISHAM Working Group ONYGENALES. All researchers, students, clinicians, laboratorians and public health professionals across biomedical disciplines, who are interested in current developments in dermatophyte and onygenalean fungi research, are cordially invited!

What we do?

Onygenales WG creates a platform for free exchange of ideas and research results. It brings together scientists, clinicians and others connected by their common interests on diverse aspects of research in dermatophytes, dimorphic and keratinophilic fungi.

Why to participate?

Get a taste of what research in a field is all about and what are the future directions and priorities. Don’t miss the unique opportunity to meet and connect with experts from the whole world. Get feedback on your projects and receive advice by the experts in a friendly and casual atmosphere.

TOPICS


TAXONOMY & PHYLOGENY

Taxonomy of dermatophytes, dimorphic and keratinophilic fungi; new markers.


DIAGNOSTICS & TREATMENT

Advances in the diagnostic approaches and treatment strategies.


ANTIFUNGAL RESISTANCE

Resistance mechanisms, spread of resistance, susceptibility testing.


EPIDEMIOLOGY & CLINICS

Changes in the epidemiology and clinical manifestations of infections.


EMERGING PATHOGENS

Emerging and re-emerging pathogens, their surveillance and control.


VIRULENCE & PATHOGENESIS

Virulence factors, pathogenesis mechanisms, experimental models.


ECOLOGY & RESERVOIRS

New data about ecology and environmental sources of pathogens.


OMICS TECHNOLOGIES

Omics technologies and their implementation into various aspects of research.

Speakers

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ON-SITE PARTICIPANT
69.00 EUR

Two Days Workshop
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Joint-Workshop Dinner
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ONLINE PARTICIPANT
20.00 EUR

Two Days Workshop – Online Stream
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Program

Final program will be available on August 20, 2020.
Day 1
10 Sep 2020
Day 2
11 Sep 2020
8:30 - 9:45

Registration on-site

Opening words

HAZAL KANDEMIR
Vit Hubka
VIT HUBKA
10:00 - 11:30

Session 1: Antifungal resistance and susceptibility testing

EUCAST Susceptibility testing of microconidia-forming dermatophytes

Antifungal drug resistance in dermatophytes was first reported shortly after the turn of the millennium and has today been reported in Trichophyton and occasionally in Microsporum, but not in Epidermophyton...
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MAIKEN C. ARENDRUP

Terbinafine resistance of dermatophytes in India and Germany

Resistance of dermatophytes against antifungal agents was not perceived as a problem for decades. Therapy failure in onychomycosis or tinea capitis was never related to a reduced in vitro susceptibility...
Read More
PIETRO NENOFF

In vitro antifungal susceptibility testing and point mutations in the squalene epoxidase gene of Trichophyton mentagrophytes/interdigitale complex from China, India and Australia

During the past decade, a severe outbreak has taken place in India of terbinafine-resistant strains in the Trichophyton mentagrophytes / T. interdigitale complex. In this study, a total of 145...
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Xue Kong

Multiple resistances of Indian T. mentagrophytes squalene epoxidase double mutants

The Indian ITS genotype VIII T. mentagrophytes population shows a high amount of different erg1 (ergosterol) mutants encoding for squalene epoxidase, which catalyzes the first step of ergosterol biosynthesis. Implication...
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Anke Burmester

First case of tinea corporis due to Trichophyton mentagrophytes genotype VIII in South-East Europe (Greece)

Changes in dermatophyte epidemiology in Europe should be continuously monitored and reported, in view of the increased human mobility from and to endemic areas and the increased cohabitation of humans...
Read More
Michael Arabatzis

Epidemiological survey of dermatophyte resistance in Europe

Dermatophytosis, tinea, is a common infection and world-wide distributed. It has until recently been considered a mild infection and easy to treat. Unfortunately, an epidemic of atypical widespread recalcitrant and...
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Ditte M. Lindhardt Saunte
11:30 - 11:55

COFFEE BREAK

11:55 - 13:00

Session 2: Taxonomy of keratinophilic and dimorphic fungi

An Overview of Molecular Phylogeny of Onygenales

Members of the order Onygenales can be found on diverse sources. Before the molecular techniques were introduced in Mycology, identification and classification of the species were based on mainly morphological...
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HAZAL KANDEMIR

New genera of Onygenales: their morphology, ecology and molecular phylogeny

Order Onygenales is unique in the sense that most of its members have affinity towards keratin. This feature of keratin degradation is rarely found in any other order in the...
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RAHUL SHARMA

New Keratinophyton species (Onygenaceae) from Europe

Four new Keratinophyton species (Ascomycota: Pezizomycotina, Onygenales), isolated from soil samples originating from Europe (Austria, Italy and Slovakia) are described, illustrated and presented here. The new taxa are well supported...
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Roman Labuda
13:00 - 14:00

Lunch Break

14:00 - 15:00

Session 3: Taxonomy of Dermatophytes

Revised taxonomy of zoonotic pathogens in the Trichophyton benhamiae complex

Species of the Trichophyton benhamiae complex are predominantly zoophilic pathogens with a worldwide distribution. These pathogens have recently become important due to their epidemic spread in pets and pet owners....
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Vit Hubka
VIT HUBKA

Molecular and physiological analysis of the T. mentagrophytes / T. interdigitale species complex using a global set of strains

A severe outbreak of highly virulent and multi-resistant dermatophytosis is ongoing in India. There is a debate about the correct identification of the etiologic agent: Trichophyton mentagrophytes or T. interdigitale....
Read More
Chao Tang

Deciphering the composition of dermatophyte complexes

In recent years many advances have been made in clearing up the phylogenetic relationships within the family Arthrodermataceae. However, certain closely related taxa still contain poorly resolved species boundaries. Here...
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Ann Packeu
ANN PACKEU
15:00 - 15:20

Coffee Break

15:20 - 16:30

Session 4: Virulence factors and pathogenesis

In vitro evaluation of enzymatic virulence activities and antifungal susceptibility profile of Microsporum canis strains from various sources

Microsporum canis is one of the major pathogenic and most prevalent dermatophytes of domestic animals causing tinea capitis which differs from one country to another worldwide. To have an effective...
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Chioma I. Aneke

Virulence factors of epidemically spreading population of the Trichophyton benhamiae clade

White and yellow strains of Trichophyton benhamiae are well known pathogens of pet animals with frequent transmission to humans. Based on the recent data, white phenotype strains form three subgroups...
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Lenka Machová

Spherule remodeling and endospore development in the fungal pathogen, Coccidioides posadasii

Coccidioides immitis and C. posadasii are soil dwelling dimorphic fungi found in North and South America. Inhalation of environmentally produced conidia results in infection. Coccidioides spp. make specialized parasitic spherules,...
Read More
Bridget M. Barker

Histoplasma relies on gluconeogenic substrates to circumvent nutritional limitations within macrophages

Microbial pathogens rely on exploiting host nutrients to proliferate during infection. Intracellular pathogens, particularly those exclusively living in the phagosome such as the primary pathogen Histoplasma capsulatum, must be able...
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Qian Shen
18:00

Workshop dinner

9:00 - 10:10

Session 5: Emerging and zoonotic pathogens

Ringworm in wild European hedgehogs: clinical and therapeutic approach in a French wildlife rehabilitation centre

The upraising number of European hedgehogs (Erinaceus europaeus) admitted every year to wildlife rehabilitation centres in Western Europe might be a source of concern to animal and public health since...
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Verónica Risco-Castillo

Emergent fungal pathogens of captive reptiles in Russian Federation

Exotic reptiles took up a niche of popular companion animals in recent decades. However, the importance of fungal infections in reptiles is still underestimated in many cases. Mycoses in reptiles...
Read More
Alla G. Gaynullina

German-wide analysis of the prevalence and the proliferation factors of the zoonotic dermatophyte Trichophyton benhamiae

For about 10 years, a new variant of the pathogen Trichophyton (T.) benhamiae has appeared in Germany, characterized by a previously unobserved culture phenotype with a strong yellow reverse. A...
Read More
Yvonne Gräser
10:10 - 10:35

Coffee break

10:35 - 11:45

Session 6: Epidemiology

Belgian national survey on tinea capitis: epidemiological considerations

Tinea capitis (TC) is a superficial infection of the scalp caused by dermatophyte fungi which affects mainly prepubescent children. This last decade, a huge increase of African anthropophilic strains causing...
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ROSALIE SACHELI

Screening for terbinafine resistance in clinical dermatophyte isolates in Australia

Onychomycosis is frequently recalcitrant to treatment. The issue of terbinafine resistance has been raised by the current epidemic of dermatophytoses in India. Laboratory identification and microdilution susceptibility testing of the...
Read More
Steven Hainsworth

Eight-year molecular epidemiology of dermatophytosis in the Czech Republic and antifungal susceptibility patterns of selected species

A large-scale molecular epidemiology project has been conducted by a collaborative network of 8 institutions in the Czech Republic. Isolates and associated data obtained between 2012 and 2019 were analysed....
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PAVLINA LYSKOVA

Trends in the epidemiology of dermatophytes and related infections in Iran

The changes in the epidemiology of dermatophyte fungi and related infections (Dermatophytosis or tinea) in Iran are presented here. A comprehensive literature search was carried out. We found that mycological...
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ALI REZAEI-MATEHKOLAEI

Epidemiology of dermatophyte infections in Slovenia

Several countries reported differences in dermatophytes epidemiology that have been associated with migration from endemic areas. We analysed notified dermatophytoses/tinea infections (N=52 600) in Slovenia 2006–2019. Tinea most frequently affected...
Read More
MAJA SUBELJ

Molecular epidemiology of dermatophytes in Iraq and Cambodia

Part 1 Iraq – Objectives: From Iraq, few data on the occurrence of dermatophytes are available. A study on prevalence of dermatophytes in Baghdad, Iraq, was done. Patients and methods:...
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Silke Uhrlaß
11:45 - 12:45

Lunch Break

12:45 - 14:05

Session 7: Diagnostics and treatment approaches

Evaluation of the new Id-fungi plates medium from Conidia® for MALDI-TOF MS identification of filamentous fungi

The first purpose of this study was to compare the efficiency of mould/dermatophytes identification by matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) using a new medium...
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MARIE-PIERRE HAYETTE

Inactivation of dermatophytes and treatment of onychomycosis using non-thermal plasma

Onychomycosis is the most common nail disorder. Current treatment of this infection does not achieve ideal results in the efficacy and has the potential for adverse effects. The aim of...
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Vladimír Scholtz
RADIM DOBIAS

Dealing with Histoplasma and Paracoccidioides in non-endemic areas

Histoplasma and Paracoccidiodes are both thermodimorphic fungi and endemic in some geographic areas. Paracoccidiomycosis is a systemic fungal disease occurring in Latin America and it is more prevalent in South...
Read More
Cristina Veríssimo

The new Atlas of Clinical Fungi

This Autumn, the Atlas of Clinical Fungi will appear in print. With several thousands of pages in full colour covering more than 700 fungi, the book provides a wealth of...
Read More
SYBREN G. de HOOG
14:05 - 14:30

Coffee Break

14:30 - 16:05

Session 8: Population genetics and genomics

Unravelling the genetic variability of Microsporum canis

Microsporum canis is the most common dermatophyte in cats and dogs, with cats considered to be the most important reservoir hosts. M. canis is diffused worldwide and plays an important...
Read More
Andrea Peano

Genotyping of Russian isolates of fungal pathogen Trichophyton rubrum, based on simple sequence repeat and single nucleotide polymorphism

The Trichophyton rubrum species group consists of prevalent causative agents of human skin, nail and hair infections, including T. rubrum sensu stricto and T. violaceum, as well as other less...
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Ivan Mikhailovich Pchelin

Population biology of Trichophyton erinacei, an emerging cause of dermatophytosis

Trichophyton erinacei is increasingly reported as a cause of dermatophytosis in wild and pet hedgehogs, their breeders, and owners worldwide. The pathogen was originally described in the European hedgehog (Erinaceus...
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ADELA CMOKOVA

Onygenalean fungi detected in Martes zibellina by culturomics and NGS approaches

The aim of the study was to detect potentially pathogenic fungi in skin lesions of wild sables Martes zibellina from Siberia region of Russia. Outbreaks of mass skin lesions in...
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ROMAN S. OVCHINNIKOV

Detection and monitoring of Coccidioides spp. in the environment

Valley fever or coccidioidomycosis is a life-threatening fungal infection caused by inhalation of arthroconidia (airborne particles) of the two closely related species, Coccidioides immitis and C. posadasii, present in soil...
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Anastasia P. Litvintseva
16:05 - 16:20

Closing Remarks

PRAGUE

Czech Republic
Snemovni 7, Prague 1, Czech Republic
+420-739-663-218vit.hubka@natur.cuni.cz

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